Our proposition is that suboptimal GSH levels associated with so many chronic diseases is not due to a cysteine undersupply but an impairment in one of the multiple control mechanisms of the GCL enzyme
These findings highlight the regulatory role of MAPKAPK2 in the oxidative stress response of vitiligo melanocytes and underscore its functional relevance in vitiligo pathogenesis, providing a rationale for future targeted therapies
In order to evaluate the cytotoxicity of Ti nanoparticles, Fer-1, UA, and Erastin on these cells, different concentrations were added and incubated
Various causes, including exogenous and endogenous stress factors, an imbalance between prooxidants and antioxidants, disruption of antioxidant pathways, and gene polymorphisms, lead to the overproduction of reactive oxygen species
SF3B3-regulated mTOR alternative splicing promotes colorectal cancer progression and metastasis
W.JenkinsB