Patients with significant visceral fat burden see the clearest benefit from tesamorelin
Based on the profile of participants enrolled in retatrutide trials to date, the drug appears most relevant to adults living with obesity (BMI 30 kg/m) or those who are overweight (BMI 27 kg/m) with weight-related health conditions such as type 2 diabetes, hypertension, dyslipidaemia, or obstructive sleep apnoea
Muscle Nerve 23:336343 Krarup C (1991) Abnormalities in the sensory action potential in patients with amyotrophic lateral sclerosis
The author holds equity interest in RNA Therapeutics Inc, DEI Biopharma Inc, Abyolo, and BioRx Inc, but none of these create any conflict of interest for this paper
I forgot how I stumbled across them
Discuss lifestyle interventions first and frame medications as adjuncts