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Because they are not the same medication
Tirzepatide is a medication designed to help people with type 2 diabetes improve blood sugar control
CrossRef Efficacy of Personalized Diabetes Self-care Using an Electronic Medical RecordIntegrated Mobile App in Patients With Type 2 Diabetes: 6-Month Randomized Controlled Trial Eun Young Lee, Seon-Ah Cha, Jae-Seung Yun, Sun-Young Lim, Jin-Hee Lee, Yu-Bae Ahn, Kun-Ho Yoon, Min Kyung Hyun, Seung-Hyun Ko Journal of Medical Internet Research.2022
Severe nausea, vomiting, inability to eat, extreme fatigue, or persistent digestive distress suggest the dose may be too high
Users who experience aches during the first few weeks and then see them resolve typically also report strong appetite suppression and steady weight loss during that same period
Useful target-engagement readouts may include reduced 1-methylnicotinamide formation, changes in nicotinamide-related metabolites, and confirmation that the selected cellular or tissue model expresses NNMT at a level relevant to the experimental question
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