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For example, GSSG is readily produced in cells in response to exogenous oxidants, supporting the concept that GSH acts as a reductant in these situations 21,66

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This is present in all cells but is particularly concentrated in the liver

van den Dobbelsteen et al., 1996) and with the subsequent conflicting notion that chemical depletion of GSH was not, however, sufficient to induce the apoptotic process (Ghibelli et al., 1999