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[12] [13] Patients should note that MHRA marketing authorisation and NICE recommendation are separate processes: a medicine may be licensed before NICE has completed its appraisal, and NHS commissioning is guided by NICE recommendations

How Semaglutide Works in the Body Semaglutide, the active ingredient in Wegovy, is a GLP-1 receptor agonist that mimics glucagon-like peptide-1a natural hormone that regulates appetite, digestion, and blood sugar levels

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Bischoff-Ferrari et al 2025)

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