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Which medicines can affect vitamin B12
Divide the dose 60/40 or 50/50 between morning (fasted) and evening (at least 2 hours after eating)
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Injection Administration: The injection is administered intramuscularly, typically in the arm, thigh, or buttocks
Additionally, the NNMT substrate nicotinamide 12 is metabolized by the microbiome 56,57 , and thus NNMTi may modulate substrate availability, potentially influencing microbial metabolic capacity to drive the NNMTi-mediated weight loss
Patients frequently report an energy change in the first day or two, which is most plausibly B12 in deficient patients, and expectation in everyone else
