In anaerobic conditions, glucose undergoes glycolysis to form lactate, generating 2 ATP per molecule
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But now, instead of a sweetness, "they taste bland," she says
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GLP-1R activation exerted antifibrotic effects by disrupting the interaction between the NLRP3 inflammasome and PFKFB3-driven glycolysis, and subsequently inhibiting lactate-mediated histone lactylation to reduce the expression of profibrotic genes in activated lung fibroblasts (Fig
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