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Decide as a team who will verify the last dose time, how to handle intraoperative glucose, and how you will flag any unexpected gastric contents
They identified 16,058 patients with MASLD and diabetes who initiated GLP-1RAs between January 2006 and June 2022 and matched them to an equal number of patients who initiated dipeptidyl peptidase 4 inhibitors (DPP-4is) in the same month
Diet changes or weight loss: You might find yourself eating differently on Ozempic
However, the lack of standardized formulation for lipotropic injections presents a significant concerncompounding pharmacies may include additional ingredients such as L-carnitine, lidocaine, other B vitamins, or amino acids that have not been evaluated in combination with GLP-1/GIP agonists
They want to know how likely they are to see a noticeable change
Future GLP-2 trials in IBD should stratify patients by disease phenotype (mucosal UC, inflammatory CD, stricturing CD) and incorporate serial cross-sectional imaging to monitor for stricture progression, given the mechanistic link between GLP-2R signaling through subepithelial myofibroblasts and intestinal fibrogenesis
