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1B) genes from A549 and H460 cells treated with 1 M A-485 for 6 h
Notably, the present narrative review is an extension of a previous review article that covered polyphenols and/or phytoestrogens that included daidzein, equol, genistein, and resveratrol as supplemental therapies for skin aging, which was published in Dermatology and Therapy earlier this year by Lephart (2025) [9]
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The chemical works especially well on pigmentation caused by hormones, and it works even better on skin discoloration caused by pregnancy
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