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GLP-1 agonists promote satiety, delay gastric emptying and reduce hunger signals, making it easier to maintain a caloric deficit

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Firstly, the impact is partly due to ameliorating caspase-3 and Bax activity and upregulating Bcl-2 [156]

It also delays gastric emptying, so meals feel satisfying for longer

GLP-1s have an anti-inflammatory effect and influence cravings and food preference patterns to the degree that these medications are being studied for alcohol use and substance-use disorders. GLP-1s have become a way to drive unprecedented weight loss

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