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10.1007/s00125-017-4315-2 94
4d) suggests significant changes in the expression of genes related to a range of metabolic signalling networks, including lipid, protein, nucleotide, carbon and reactive oxygen species metabolism
Cellular metabolism regulates contact sites between vacuoles and mitochondria
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Likewise, metformin and atorvastatin plasma profiles had AUC ratios close to 1.0 and shared the same characteristics of being slightly right-shifted and with lowered maximum concentrations (10 and 38%, respectively)
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