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Furthermore, it is likely that the optimal ratio of receptor agonism across target receptors varies between individuals

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Compared with untreated controls, microsomal protein concentrations were increased after twenty-eight days of treatment in C57BL mice, after four and twenty-eight days of treatment in C3H mice, after four days of treatment in B6C3F1 mice, and with no effect of treatment in C3B6F1 mice

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10.1016/j.ejphar.2011.05.038 31 IlicS.DrmicD.ZarkovicK.KolencD.CoricM.BrcicL.et al (2010)