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Another article review reported that return to baseline gastric function requires cessation of GLP-1 RA use approximately five half-lives of the GLP-1 RA (Ushakumari and Sladen 2024)

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To circumvent this bottleneck, the same group ingeniously exploited the structural similarity between fluorouridine (Fdu) and thymidine, incorporating Fdu during solid-phase synthesis to enable subsequent TME-responsive carbonate linkage with a synergistic PROTAC, yielding AS-2F-NP (Fig

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