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It was reported that MTZ binds to human plasma proteins in vitro at concentrations between 0.01 and 10 mg/L with an approximate 85% affinity (Van der Vorstenbosch and Delbressine 1988)

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Sheyn, U., Rosenwasser, S., Ben-Dor, S., Porat, Z

This type of synapse is, by far, the most utilized in the CNS and, therefore, the main target of the existing methods to visualize or quantify synapses