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One of the most consistent findings in clinical trials is a slight increase in resting heart rate , typically between 2 and 4 beats per minute
Additionally, some patients have experienced gastroparesis, a condition where stomach muscles become paralyzed, leading to digestive complications
doi:10.1146/annurev.nutr.26.061505.111223
However, in practice, investigators could only introduce a small amount of stratification and could not balance all important variables simultaneously ( Propensity score matching (PSM) was defined as the conditional probability of a subject being assigned to the treatment group given the observed covariates
Persistent symptoms mean the dose holds steady rather than going up
