Institutions like the Open Medicine Foundation have actively investigated how bypassing this broken pathway with direct methylcobalamin supplementation can help restore methylation function, reduce debilitating fatigue, and improve cognitive clarity in ME/CFS patients
Furthermore, the human body's intestinal transporters for Vitamin C (SVCT1) become saturated at higher doses
C.et al (2016)
Yet, supplementation with folic acid and other B vitamins does appear to lower the risk of stroke
Metabolic and Cardiovascular Benefits By reducing systemic inflammation and improving insulin sensitivity, FOXO4-DRI supports metabolic health, lowering risks associated with type 2 diabetes and cardiovascular disease
If you use peptides sourced from gray-market retailers, you wont know whether its a safe or smart option for your circumstances, or if other paths should be explored first