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The skin is cleaned with an antiseptic wipe at the injection site, usually the upper outer arm, and the intramuscular injection is given with a fine needle in around ten seconds

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466 One study proposed a novel mechanism wherein postprandial GLP-1 release, under normal physiological conditions, inhibits the activity of chemosensory cells in the carotid body, thereby counteracting sympathetic excitability mediated by elevated blood glucose or insulin levels

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Fifth, regulatory and reimbursement varies across countries and regions, affecting its widespread implementation (148)