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Meanwhile, GLP-1 receptor agonists and GIP medications are injectable hormone medications that have been used in the treatment of type 2 diabetes and, more recently, for the treatment of obesity with great success
Human Reproduction, 37 (1), 614
While both semaglutide and liraglutide hydrogel-based formulations were shown to improve glucose as well as body weight control, we found that semaglutide-loaded hydrogel formulations exhibited high C max values within one day of treatment and high drug exposure over the first week of therapy, which is likely to be poorly tolerated in humans
Nature 440, 10691072
NICE recommends lifestyle and dietary support alongside GLP-1 treatment (NICE NG28), with patients benefiting from comprehensive dietary counselling to optimise treatment outcomes and minimise side effects
That slowing can be helpful for weight loss, but it may also affect the absorption of oral medications, including thyroid medication, in some patients
