Supplementation with vitamin B 12 increases the efficiency of reprogramming both in mice and in cultured cells, the latter indicating a cell-intrinsic effect
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This results in a more consistent, non-jittery improvement in metabolic efficiency
While very high oral doses (1,000 to 2,000 mcg) can achieve some passive absorption without intrinsic factor roughly 1% of the dose is absorbed passively many clinicians prefer the reliability and rapid correction offered by injections in this population
Supportive treatment for joint pain relief
This is the main reason why celebrities like Charlize Theron, Justin Timberlake and even Madonna are getting vitamin B12 injections regularly