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Severe Health Risks Acromegaly-like Effects: Similar to Growth Hormone (GH) abuse, IGF-1 LR3 abuse can lead to acromegaly, a long-term condition in which body tissues get larger over time

5.2 Liking: evidence for subjective taste and eating-experience endpoints Compared with sensory endpoints, evidence relating to the effects of GLP-1RAs on subjective hedonic evaluation (liking) is more abundant and derives mainly from patient-reported outcomes (PROs) and eating-experience-related questionnaire studies

Inconsistent semaglutide dosing can compromise both treatment efficacy and safety

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References: Blackman, M

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