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Elevated blood concentrations of uric acid, occasionally resulting in attacks of gout in susceptible individuals, have also been observed with high-dose nicotinic acid therapy (126)
Statistical analysis All measurements in cell culture were carried out, at least, in triplicate, and the results are expressed as the means.e.m
10.1093/rb/rbab074 23 GuX.LiZ.SuJ
PMID: 33614828
The aim of this study was to prove our hypothesis that A-GSH functionalization increases brain endothelial internalization and BBB permeability of polymeric nanoparticles coupled with active agents, namely dopamine and ibuprofen, which have low brain penetration