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In obese patients, GLP-1 infusion significantly increased excretion of sodium (by 60%), calcium (by 60%) and chloride (by 44%) and significantly decreased excretion of H + (by 75%)

Most women begin to feel improvements within a few weeks, with optimal results around 3 months after starting therapy

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These effects typically occur during dose initiation or escalation and often improve as the body adapts to the medication

The analysis includes data from more than 6,000 patients a remarkable collaborative effort