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In a study in subjects with different degrees of hepatic impairment, no clinically relevant change in semaglutide pharmacokinetics (PK) was observed [see Clinical Pharmacology (12.3)]

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Best time for injectable semaglutide Injectable semaglutide can be taken at any time of day

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This titration process gives your body time to adjust to the medication and minimizes gastrointestinal side effects that drive many people to quit too early

Start your intake The Physiology Behind GLP-1-Related Bloating GLP-1 receptor agonists slow gastric emptying and increase satiety signaling in the brain