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A GPx standard solution was prepared by dissolving 417 mg of GPx in 100 mL of 100 mM phosphate buffer at pH 7.0

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The NOD mice were treated with either vehicle (nonspecific scrambled MOTS-c peptide), MOTS-c (0.5 mg kg 1 per day, intraperitoneally (i.p.)) 7 , exendin-4 (2 g kg 1 , two times a day, i.p.) or both 23