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In a 9-month monkey oral toxicity study, all female monkeys in the high-dose group showed minimal-to-slight periportal hepatocyte vacuolation

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The authors fused BioID (or BioID2) to a bait protein using endogenous gene tagging in Toxoplasma and then identified interacting and neighboring proteins within subcellular compartments through in vivo biotinylation, streptavidin affinity purification, and mass spectrometry [83]

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The timing of motivational difficulties relative to lifestyle changes provides valuable diagnostic information