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Foods that are high in vitamin B12 include organ meats, dairy products, eggs, meat, poultry, and seafood

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Vitamin B12 deficiency is increasingly recognised as a global public health concern, particularly in developing countries and among high-risk populations

In parallel, advances in peptide chemistry and structural biology have enabled the design of aggregation inhibitors, receptor-selective neuropeptide analogues, and cell-penetrating or brain-targeted peptide conjugates that modulate key pathways, including proteostasis, insulin and incretin signaling, neurotrophic support, and microglial activation

Conditions like irritable bowel syndrome (IBS), inflammatory bowel disease (IBD), small intestinal bacterial overgrowth (SIBO), and leaky gut syndrome are not only common but often underdiagnosed or mismanaged

For all real-time RT-PCR experiments, each condition was in triplicate