There is no formal contraindication, but safety depends on individual disease activity and symptom control
[1] [2] Some patients report feeling more tired when starting Saxenda, particularly if they are also following a reduced-calorie diet
However, if the LECs escape their confinement and migrate onto the posterior capsule, they would first migrate and proliferate as they are relieved from contact inhibition (83, 302), then would be expected to induce lens fiber cell differentiation which would result in Elschnigs pearls as the anatomical signals (and space) for normal fiber cell morphogenesis are absent (96, 303)
Retatrutide, an in-development weight loss treatment, is not currently licensed for use in the UK
Both substances affect blood sugar and liver function
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