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A well-matched population was found in the GLP-1RAs vs metformin groups ( n =47,097 each) after PSM (ESM Figs 2 and 3)
Mild nausea without weight loss is expected during week one at low doses
Researchers who have experienced a mid-protocol supply disruption, where they could not obtain their peptide for two or three weeks mid-study, understand this viscerally
& Eldeghaidy, S
Additional factors, such as membrane potential and, critically, the presence of lipopolysaccharides or teichoic acids, are likely involved
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