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Certain individuals may be more susceptible to gastrointestinal side effects from semaglutide, including: Patients with diabetes-related nerve damage (autonomic neuropathy) Individuals with known gastroparesis Those taking other medications that slow gastric emptying Patients who rapidly escalate doses Careful screening and gradual dose adjustments are important to minimize risk

This interval provides ample clearance time given the peptide's short half-life and allows monitoring for any delayed effects

Semaglutide and cardiovascular outcomes in obesity without diabetes

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