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Full quantification may be obtained by applying a suitable pharmacokinetic model, allowing several physiological parameters to be derived, including the transfer constant (Ktrans, Box 1), fractional plasma volume (Vp), and fractional volume of the tissue extracellular space (Ve) ( 3.2.1.2

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Altas concentraciones en forma tpica pueden causar irritacin o sequedad temporal de la piel