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A significant age group sex interaction was observed, with pomegranate extract reducing plasma TMAO AUC in female participants of premenopausal age and male participants while showing opposite effects in female participants assigned to the Older (postmenopausal age) group

As expected, the engagement mode of Cagri with AMYRs is mainly conserved with that of rAmy and characterized by the formation of a bypass motif (residues S19 Cagri- P25 Cagri ) (Fig