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Monitoring Regular physician check-ins (every 2 to 4 weeks during titration, monthly during maintenance) track GI tolerance, weight loss progress, body composition, energy levels, and any adverse events

NO, as a lipophilic molecule, easily diffuses from endothelium into adjacent vascular smooth muscle cells (VSMCs) and binds to the prosthetic haem group of soluble guanylate cyclase (sGC), thus activating the enzyme [7]

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