Lund PJ, Gates LA, Leboeuf M, Smith SA, Chau L, Lopes M, et al
Anecdotal reports of subcutaneous use exist, but no formal stability, bioavailability, or safety data supports this route
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Its important to approach skin lightening with realistic expectations
\Anti-inflammatory: Increases IL-10, reduces systemic inflammation
Patient selection criteria are not well-established, and determining which patients are most likely to benefit from these therapies requires clinical judgment based on limited evidence