Table 1 Efficacy of DPP-4 inhibitors in the clinical phase III programmes with at least 52 weeks duration as add on therapy to metformin compared to sulfonylureas
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The hormone delivers this benefit via several interlocking effects
233 The TRAVERSE trial, described above, provided additional evidence for TRTs safety in men with hypogonadism and existing or high risk of cardiovascular disease
Singh S, Facciorusso A, Singh AG, VandeCasteele N, Zarrinpar A, Prokop LJ, et al
Some preclinical studies have explored sequential administration protocols designed to mimic this temporal pattern