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BGI (Yantian District, Shenzhen, China), an established contract research organization, isolated DNA from the remaining cecal samples and generated a metagenomic 16s rDNA amplicon library

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Amylin analogs like cagrilintide appear to act via hindbrain satiety circuits and may also influence reward-related pathways involving AgRP and POMC neurons

The Science of the Total Environment, 553 , 196203

Previous AngIV analogs, while showing promise in animal models of dementia, were hindered by poor metabolic stability indicated by a short half-life, and an inability to cross the BBB due to their peptide nature