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Studies to clarify the riskbenefit ratio of DKA and improved cardio-renal outcomes with SGLT2i use in type 1 diabetes are required to help inform future guidelines and standardise clinical practice

As patients lose weight on GLP-1 therapy, reductions in fat massespecially around internal organscan enhance the body's responsiveness to insulin

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Treating the medication itself as the signalwithout understanding why its prescribedis where misinterpretation creeps in