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Regarding this, GLP-1RAs inhibit ER stress and promote protein folding via endoplasmic reticulum oxidoreductase (ERO1) in an AMPK-dependent manner, as well as mediating the process of mitochondrial fusion [115, 151]
Work down this troubleshooting ladder before considering any dose change and always inside the research-use-only, escalate-slowly framing: Confirm you are actually at a maintenance dose
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Biomolecules 15 (2), 292 (2025)
