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Micro BCA Protein Assay Kit, H 2 DCFDA (H 2 -DCF, DCF), C11-BODIPY (581/591), MitoSOX Red Mitochondrial Superoxide Indicator, MitoTracker Red CMXRos, and Dulbeccos modified Eagles medium (High glucose, no glutamine, no methionine, no Cys 2 ) were purchased from Thermo Scientific (Waltham, MA, USA)

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However, it should also be remembered that Cr supplements are often taken in large amounts (2030 gram per day for several days) and result in elevated plasma Cr levels that can reach 23 mM [8] while Cr concentration in muscles is in the range of 2040 mM [62]

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During malignant transformation, cancer cells modify the consumption and processing of glutamine to sustain cell growth and proliferation

Br J Pharm Res