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Monitoring for subtle improvementslike smoother movement, better sleep, or reduced itchingcan help determine if the peptide is working

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Ongoing studies will provide more complete safety data over several years

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SGLT2 inhibitors and GLP-1 agonists should be used as early as possible in the diabetes course to provide the most cardiac benefit, Joanna Khatib, MBBS, an endocrinology fellow at Tulane University School of Medicine, told Healio

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8 Challenges in clinical application Considering the enumerated benefits of GLP-1RA compared to other glucose-lowering drugs including the reduction in HbA1c and weight reduction benefits alongside decreased risk for hypoglycaemia (122) it is not cost effective if used in combination with another incretin (107)

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The Bottom Line Who Needs a GLP-1

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In this case, theyre your only option

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