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Cardiovascular protection: Noveltreat is indicated for adults who are overweight or obese with established heart disease, helping reduce the risk of severe cardiovascular events

However, these studies also report side effects and some participants dropping out

These tend to show up when starting the medication or increasing the dose, and often become easier to manage over time

Lack of Expected Benefits If you have been taking magnesium supplements for several months without experiencing expected improvements in symptoms such as muscle cramps, sleep disturbances, or other concerns that prompted supplementation, discuss this with your GP

doi:10.1016/0190-9622(90)70273-k

The obesity trial measured its primary endpoint at 24 weeks and kept following participants to 48 weeks, with average weight still declining at the highest dose by the end (Jastreboff et al., 2023)