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But sustained activation, the kind tirzepatide provides week after week, appears to allow the brain to adapt and may ultimately shift mood regulation in a positive direction

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Clinical observations align with these mechanisms

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These effects may potentially provide a new therapeutic solution for stroke with specific beneficial effects on the CNS (i.e., reperfusion, amelioration of neuronal damage leading to recovery in the absence of memory, motor, and coordination deficits, and expression of specific genes in the hippocampus)

Decrease of blood flow below 1 ml/g/min causes total cellular death in the affected area