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Karakteristike: svakodnevna primena (za razliku od nedeljnih injekcija kod semaglutida) slabiji efekat u poreenju sa novijim lekovima i dalje efikasan kod odreenih pacijenata Liraglutid je prethodna generacija GLP-1 terapije

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When patients lose a substantial amount of weight on GLP-1s, they experience volume loss in these facial fat pads and appear sunken in, often looking older than their actual age

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discontinue if weight loss is less than 5% Regular weight measurements and BMI calculations Monitoring for adverse effects, particularly gastrointestinal symptoms Blood pressure and cardiovascular risk factor assessment Periodic blood tests to monitor metabolic parameters For patients with diabetes who are taking insulin or sulfonylureas, doses of these medications may need to be reduced when starting GLP-1 receptor agonists to prevent hypoglycaemia