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During our study, participants experienced shifts in both physical symptoms and emotional patterns

The kidneys and nervous system are similarly sensitive to biochemical imbalances over time

presence of any co-occurring diagnoses influenced the results, in another post hoc analysis we split each group into two subgroups: those that had no other diagnosis, and those that did have one or more additional diagnoses (for hypothyroidism, N = 19 and N = 21

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Neuroinflammation induced by TNF- can affect the signaling of neurotrophins such as NGF and BDNF, which are essential for neuronal survival, growth, and plasticity (Saghazadeh and Rezaei 2017)

Statistical analyses were conducted with IBM SPSS Statistics for Windows, version 25 (IBM Corp., Armonk, N.Y., USA)