References Heffernan M, Summers RJ, Thorburn A, Ogru E, Gianello R, Jiang WJ, et al
Herbs and dietary supplements in the prevention and treatment of cardiovascular disease
This research showed that GSH supplementation of amino acids (including L-glycine) and micronutrients (including vitamin C, vitamin E, and magnesium), as well as specific dietary patterns (vegetarian, the Mediterranean diet, and the DASH diet) had the potential to raise glutathione concentrations, which in turn slowed the rate of tissue deterioration
Compared with GPX1-3, GPX4 is also involved in the reduction of complex membrane-associated phospholipid hydroperoxides such as phosphatidylcholine hydroperoxide and cholesterol hydroperoxide, in addition to reacting with soluble, low molecular weight hydroperoxides such as t-butyl hydroperoxide and cumene hydroperoxide [68]
Accessed Mar 2022.
I recommend it as the first supplement for almost every perimenopausal woman I see experiencing mood instability, irritability, or sleep disruption
