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62 In this context, our results support a model in which Trim37 -deficient PGCs exit the germline program and enter an aberrant somatic-like state marked by partial and heterogeneous activation of multiple somatic gene programs, rather than bona fide lineage-restricted transdifferentiation

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The abundance of TGR mRNA was greatly reduced by dsRNA treatment while the control gene GAPDH was unaffected

In IBD, acetyl-L-carnitine improves immune tolerance by decreasing the ratio of Th17 cells and macrophages.[ref] Inborn errors of metabolism: Genetic mutations and carnitine Genetic mutations in the genes involved in the carnitine shuttle can cause inborn errors of metabolism for long-chain fatty acids