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As of 2024, there is no established clinical connection between GLP-1 receptor agonists and endometriosis treatment
Roches 3,500 GPUs thus represent a huge capital expenditure (costing hundreds of millions), but if they shave years off a blockbuster drug development, the ROI could be orders of magnitude in revenue (a successful new obesity drug can make ~$1015 billion per year for its maker)
The lowest dose of orforglipron resulted in less than 8 percent loss of body weight, or about 18 pounds, and the middle dose led to a 9 percent reduction, or 21 pounds
If you struggle with food noise, you know how relentless it can feelthose frequent and intrusive thoughts about eating that crowd your mental space
2004, pp
Varney JL et al
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