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Before traveling, patients should ask how the medication should be carried, whether refrigeration is needed, what to do about time zones, and how to keep supplies organized

These findings suggest that the additional GCG agonism in cotadutide provides direct metabolic benefits to hepatocytes beyond those achievable through GLP-1 receptor activation alone, even when caloric restriction is matched [43]

Ultimately, prescribing decisions should always be based on what is clinically appropriate for each individual patient

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