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For diabetes management, indefinite therapy is generally appropriate as long as benefits persist and the medication is tolerated

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In topical studies, side effects are minimal and usually limited to mild skin irritation in sensitive individuals

Dopamine is a crucial neurotransmitter, and its deficiency impedes neural transmission, thereby causing motor dysfunction (Klein et al., 2019)

Increased glutathione biosynthesis by Nrf2 activation in astrocytes prevents p75NTR-dependent motor neuron apoptosis

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