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Acknowledgments Among other sources, our own research is financed by the priority program 1710 which was recently founded by the German Research Foundation (DFG) to investigate enzyme-catalyzed thiol switches

The initial identification of ChaC-like enzymes in plants occurred in a 2005 study on submergence-induced genes in rice, where the upregulated gene OsCTP was noted for its high similarity to the E

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Treating just one area in isolation may not create the best result

Data sources: The Cochrane Library, MEDLINE, EMBASE.com, Science Citation Index, Google search and the China Biological Medicine Database to June 2012

The maleimide-DAC linker on CJC-1295 achieves the same result by a similar albumin-binding mechanism, extending half-life from 30 minutes to 68 days as reflected in the peptide half-life chart data above