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Deficiency is widespread, with peer-reviewed research describing it as a global health concern affecting populations across all age groups and geographies (Cashman et al., American Journal of Clinical Nutrition , 2016

P = 0.41), while male interim survival with L2-Cmu was indistinguishable from Controls (Supplementary Fig

doi: 10.1016/j.mam.2024.101273 93 HuangRChenJGuoBJiangCSunW

doi: 10.1007/BF02536638 15 DuffyS.AveryV